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  1. Early cognitive markers of the incidence of dementia and mortality : A longitudinal population-based study of the oldest old.

    Article - En anglais

    This study examines whether cognitive markers at prior examinations are indicative of subsequent dementia and mortality.

    The sample was composed of subjects aged 84-90 at baseline who were reexamined three times over a 6-year period on a comprehensive biobehavioral battery.

    Dementia was evaluated at each examination using DSM-III-R criteria.

    Results indicated that incident cases of dementia had lower cognitive scores both 2 and 4 years prior to diagnosis, compared to non-demented survivors.

    Evidence for terminal decline was also found, as people who subsequently died also had lower cognitive performance at prior examinations, compared to non-demented survivors.

    The findings suggest that mild cognitive dysfunction is an important clinical finding among the oldest old and mav herald either the onset of dementia or mortality.

    Mots-clés Pascal : Démence sénile, Incidence, Epidémiologie, Trouble cognition, Marqueur, Mortalité, Vieillard, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative

    Mots-clés Pascal anglais : Senile dementia, Incidence, Epidemiology, Cognitive disorder, Marker, Mortality, Elderly, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0146278

    Code Inist : 002B18E. Création : 21/05/1997.