This study examines whether cognitive markers at prior examinations are indicative of subsequent dementia and mortality.
The sample was composed of subjects aged 84-90 at baseline who were reexamined three times over a 6-year period on a comprehensive biobehavioral battery.
Dementia was evaluated at each examination using DSM-III-R criteria.
Results indicated that incident cases of dementia had lower cognitive scores both 2 and 4 years prior to diagnosis, compared to non-demented survivors.
Evidence for terminal decline was also found, as people who subsequently died also had lower cognitive performance at prior examinations, compared to non-demented survivors.
The findings suggest that mild cognitive dysfunction is an important clinical finding among the oldest old and mav herald either the onset of dementia or mortality.
Mots-clés Pascal : Démence sénile, Incidence, Epidémiologie, Trouble cognition, Marqueur, Mortalité, Vieillard, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative
Mots-clés Pascal anglais : Senile dementia, Incidence, Epidemiology, Cognitive disorder, Marker, Mortality, Elderly, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0146278
Code Inist : 002B18E. Création : 21/05/1997.