The influence of physical activity on lung-cancer risk : A prospective study of 81,516 men and women.
Physical activity is inversely related to mortality from respiratory diseases including lung cancer.
Physical activity improves pulmonary function but its impact on lung-cancer risk has not been studied much.
During 1972-1978,53,242 men and 28,274 women, aged 20 to 49 years, participated in a population-based health survey and were followed until 31 December 1991.
We observed a total of 413 men and 51 women with lung cancer.
Leisure activity and work activity were assessed using a questionnaire in 4 categories.
In a sub-cohort, physical activity was assessed twice at an interval of 3 to 5 years.
Leisure but not work activity was inversely related to lung-cancer risk in men after adjustment for age, smoking habits, body-mass index and geographical residence (p for trend=0.01).
Men who exercised at least 4 hours a week had a lower risk than men who did not exercise [relative risk (RR)=0.71 ; 95% confidence interval (CI)=0.52-0.97]. Reduced risk of lung cancer was particularly marked for small-cell carcinoma (RR=0.59 ; 95% CI=0.38-0.94) and for adenocarcinoma (RR=0.65 ; 95% CI=0.41-1.05), with no association seen for squamous-cell carcinoma.
In the subcohort in which physical activity was assessed twice, the risk of lung cancer was particularly reduced among men who were most active at both assessments (RR=0.39 ; 95% CI=0.18-0.85).
No consistent association between physical activity and lung-cancer risk was observed among women. (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Epidémiologie, Analyse risque, Exercice physique, Relation dose réponse, Protection, Etude cohorte, Etude longitudinale, Homme, Mâle, Femelle, Sexe, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Epidemiology, Risk analysis, Physical exercise, Dose activity relation, Protection, Cohort study, Follow up study, Human, Male, Female, Sex, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0144607
Code Inist : 002B11A. Création : 21/05/1997.