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  1. Relationships between ferruginous bodies and Uncoated asbestos fibers in lung tissue.

    Article - En anglais

    Tissue was obtained from two American groups.

    The tissue was defined by ferruginous body levels of either ¾ 1 000 or>1 000 ferruginous bodies/g dry weight, and tissue was evaluated by light microscopy and analyzed by analytical transmission electron microscopy.

    Tissue was bleach digested, and uncoated asbestos fibers were classified with respect to type and size.

    In addition, some ferruginous body cores were analyzed.

    There was a wide range of uncoated fibers associated with each ferruginous body.

    A relationship was found between amosite fibers and ferruginous bodies.

    Other asbestos types were not associated significantly with the development of ferruginous bodies.

    Uncoated crocidolite fibers were not detected in these samples ; this result further emphasizes the under-appreciated exposure of Americans to amosite.

    The levels of ferruginous bodies in both groups suggest exposures above those expected in the general population.

    Uncoated chrysotile levels were below the ranges reported previously for some general populations.

    The data suggest that there is a wide variation in the ratio of uncoated to coated fibers and that the amphibole in the United States is more likely to be amosite than crocidolite.

    Mots-clés Pascal : Asbestose, Corps asbestosique, Typologie, Fibre amiante, Chrysotile, Taille, Exposition professionnelle, Homme, Toxicité, Médecine travail, Appareil respiratoire pathologie, Pneumoconiose, Maladie professionnelle, Poumon pathologie, Amosite

    Mots-clés Pascal anglais : Asbestosis, Asbestos body, Typology, Asbestos fiber, Size, Occupational exposure, Human, Toxicity, Occupational medicine, Respiratory disease, Pneumoconiosis, Occupational disease, Lung disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0144265

    Code Inist : 002B03L02. Création : 21/05/1997.