It has been shown that screening of average risk individuals reduces the incidence of colorectal cancer.
The most effective method for screening has yet to be determined in terms of cost-effectiveness, but approximately two-thirds of colorectal neoplastic lesions are within the reach of the flexible sigmoidoscope.
It has been estimated that a single such examination at the end of the sixth decade may reduce the colorectal cancer incidence by 60%. As part of a screening program for colon cancer, short colonoscopy was performed on 399 employees of a nuclear research center and 228 members of a collective settlement (kibbutz).
The examinations were carried out on individuals aged =40 years by two experienced endoscopists.
The splenic flexure or transverse colon was reached in 95% of the procedures.
Neoplastic lesions were found in 24 (6.0%) and 8 (3.5%) screenees (not significant) in the Nuclear Research Center and kibbutz populations respectively.
Polyps<1 cm in diameter were significantly more common in the Nuclear Research Center population but larger polyps and cancers were not.
In 47 Nuclear Research Center screenees with a family history positive in a first-degree relative, findings increased to 14.9% (P=0.016).
A family history of malignancy was found in 33.8% of kibbutz members but in only 11.8% of Nuclear Research Center employees.
There was no evidence to suggest that working at the Nuclear Research Center increased the risk of colonic neoplasms. (...)
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Sigmoïdoscopie, Flexible, Exposition professionnelle, Installation nucléaire, Collectivité, Etude comparative, Diagnostic, Dépistage, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Endoscopie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Sigmoidoscopy, Flexible, Occupational exposure, Nuclear installation, Collectivity, Comparative study, Diagnosis, Medical screening, Human, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Endoscopy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0137316
Code Inist : 002B13B01. Création : 21/05/1997.