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  1. Screening for colonic neoplastic lesions using flexible sigmoidoscopy in employees of a nuclear research center and members of collective settlements.

    Article - En anglais

    It has been shown that screening of average risk individuals reduces the incidence of colorectal cancer.

    The most effective method for screening has yet to be determined in terms of cost-effectiveness, but approximately two-thirds of colorectal neoplastic lesions are within the reach of the flexible sigmoidoscope.

    It has been estimated that a single such examination at the end of the sixth decade may reduce the colorectal cancer incidence by 60%. As part of a screening program for colon cancer, short colonoscopy was performed on 399 employees of a nuclear research center and 228 members of a collective settlement (kibbutz).

    The examinations were carried out on individuals aged =40 years by two experienced endoscopists.

    The splenic flexure or transverse colon was reached in 95% of the procedures.

    Neoplastic lesions were found in 24 (6.0%) and 8 (3.5%) screenees (not significant) in the Nuclear Research Center and kibbutz populations respectively.

    Polyps<1 cm in diameter were significantly more common in the Nuclear Research Center population but larger polyps and cancers were not.

    In 47 Nuclear Research Center screenees with a family history positive in a first-degree relative, findings increased to 14.9% (P=0.016).

    A family history of malignancy was found in 33.8% of kibbutz members but in only 11.8% of Nuclear Research Center employees.

    There was no evidence to suggest that working at the Nuclear Research Center increased the risk of colonic neoplasms. (...)

    Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Sigmoïdoscopie, Flexible, Exposition professionnelle, Installation nucléaire, Collectivité, Etude comparative, Diagnostic, Dépistage, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Endoscopie

    Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Sigmoidoscopy, Flexible, Occupational exposure, Nuclear installation, Collectivity, Comparative study, Diagnosis, Medical screening, Human, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Endoscopy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0137316

    Code Inist : 002B13B01. Création : 21/05/1997.