A number of prognostic factors for thyroid carcinoma have been identified, including sociodemographic characteristics, such as age and gender, and tumor characteristics, such as histology and stage.
The relative importance of these factors as independent predictors of survival for patients with papillary, follicular, anaplastic, and medullary thyroid carcinoma has been extensively studied but remains uncertain.
The authors used data collected by the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute between 1973 and 1991 to investigate prognostic factors for each of the major histologic types of thyroid carcinoma in a population-based patient series and to assess the effect of these factors as predictors of survival.
Both tumor and sociodemographic characteristics were independently associated with survival.
Patients with papillary carcinoma had the highest 10-year relative survival (0.98), followed by those with follicular carcinoma (0.92) and medullary carcinoma (0.80).
Anaplastic tumors had the lowest 10-year relative survival (0.13).
Stage at diagnosis and differentiation status were strong independent prognostic factors for each histologic type.
Advanced stage at diagnosis was a stronger prognostic factor for medullary carcinoma than for other histologic types.
Increasing age was associated with lower relative survival for each histologic type. (...)
Mots-clés Pascal : Carcinome, Thyroïde, Survie, Epidémiologie, Type histologique, Ethnie, Pronostic, Etats Unis, Amérique du Nord, Amérique, Homme, Tumeur maligne, Endocrinopathie, Thyroïde pathologie
Mots-clés Pascal anglais : Carcinoma, Thyroid gland, Survival, Epidemiology, Histological type, Ethnic group, Prognosis, United States, North America, America, Human, Malignant tumor, Endocrinopathy, Thyroid diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0136109
Code Inist : 002B21C02. Création : 21/05/1997.