The authors examined the associations between dietary factors and the risk of duodenal ulcer in a prospective cohort of 47,806 men, aged 40-75 years, who were free of diagnosed gastric or duodenal ulcer or cancer.
During 6 years of follow-up, they documented 138 newly diagnosed cases of duodenal ulcer.
They found little evidence for an important effect of fat, type of fat, or protein intake.
Higher consumption of fruits and vegetables was associated with lower risk of duodenal ulcer (relative risk (RR)=0.67,95% confidence interval (CI) 0.39-1.15 for =7 servings per day vs.<3 servings per day) after adjustment for age, body mass index, smoking, and use of aspirin or other nonsteroidal anti-inflammatory drugs.
Total dietary fiber intake was inversely associated with the risk of duodenal ulcer (RR=0.55,95% CI 0.31-0.96 for men in the highest vs. the lowest quintile of dietary fiber).
The soluble component of fiber was strongly associated with a decreased risk of duodenal ulcer (RR=0.40,95% CI 0.22-0.74 for the highest quintile).
Several age-and energy-adjusted nutrients correlated with dietary fiber were also inversely related to the risk of duodenal ulcer, but vitamin A from all sources combined (including supplements and multivitamins) was the only nutrient that was statistically significant after adjustment for other risk factors (RR=0.46,95% CI 0.23-0.91 for men in the highest vs. the lowest quintile of vitamin A intake). (...)
Mots-clés Pascal : Ulcère, Duodénum, Alimentation, Régime alimentaire, Fibre alimentaire, Vitamine, Matière grasse, Facteur risque, Epidémiologie, Homme, Etats Unis, Amérique du Nord, Amérique, Prospective, Appareil digestif pathologie, Intestin pathologie
Mots-clés Pascal anglais : Ulcer, Duodenum, Feeding, Diet, Dietary fiber, Vitamin, Fat, Risk factor, Epidemiology, Human, United States, North America, America, Prospective, Digestive diseases, Intestinal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0133243
Code Inist : 002B13B03. Création : 21/05/1997.