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  1. Evaluation of neurologic function in Gulf War veterans : A blinded case-control study.

    Article - En anglais

    Objective

    - To determine whether Gulf War-related illnesses are associated with central or peripheral nervous system dysfunction.

    Design

    - Nested case-control study.

    Participants

    - Twenty-three veterans with factor analysis-derived syndromes (the cases), 10 well veterans deployed to the Gulf War (the deployed controls), and 10 well veterans not deployed to the Gulf War (the nondeployed controls).

    Method

    - With investigators blinded to group identities, participants underwent objective neurophysiological, audiovestibular, neuroradiological, neuropsychological, and blood tests.

    Main Outcome Measures

    - Evidence of neurologic dysfunction.

    Results

    - Compared with the 20 controls, the 23 cases had significantly more neuropsychological evidence of brain dysfunction on the Halstead Impairment Index (P=01), greater interside asymmetry of the wave I to wave II interpeak latency of brain stem auditory evoked potentials (P=02), greater interocular asymmetry of nystagmic velocity on rotational testing, increased asymmetry of saccadic velocity (P=04), more prolonged interpeak latency of the lumbar-to-cerebral peaks on posterior tibial somatosensory evoked potentials (on right side, P=03, and on the left side, P=005), and diminished nystagmic velocity after caloric stimulation bilaterally (P values range from. 02 to. 04). (...)

    Mots-clés Pascal : Golfe Persique, Guerre, Complication, Trouble neurologique, Ancien combattant, Dépistage, Etude double insu, Test neuropsychologique, Evaluation, Pronostic, Analyse statistique, Homme, Système nerveux pathologie

    Mots-clés Pascal anglais : Persian Gulf, War, Complication, Neurological disorder, Veteran, Medical screening, Double blind study, Neuropsychological test, Evaluation, Prognosis, Statistical analysis, Human, Nervous system diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0126451

    Code Inist : 002B18F01. Création : 21/05/1997.