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  1. Changing patterns of bacterial nosocomial infections : A nine-year study in a General Hospital.

    Article - En anglais

    Surveillance data on 12,944 bacterial isolates derived from nosocomial infections, reported to the Department of Microbiology and Infectious Diseases of the Hellenic Air Force and VA General Hospital over a 9-year period (1986-1994), were analyzed by the use of a microbial infection control software system.

    Overall, the isolation rate of Escherichia coli decreased from 25.2% in 1986 to 18.2% in 1994 and Proteus spp. from 5.3 to 2.6%. Remarkably, Pseudomonas spp. increased from 7.2 to 11.3%, Enterobacter spp. from 1.6 to 5.1%, Klebsiella spp. from 5.9 to 7.8% and Enterococcus spp. from 3 to 7.4%. Interestingly, the above phenomenon was paralleled by a significant increase in resistance rate to various antibiotics.

    Specifically, Staphylococcus aureus and coagulase-negative staphylococci, though they did not display any significant variation in isolation rates, showed an alarming increase in resistance rate to oxacillin, from 11 and 21% in 1986 to 51 and 75% in 1994, respectively.

    Enterococcus spp. sensitivity to vancomycin remained unlatered at 90%. The above-mentioned serious shift towards more resistant bacteria should be a matter for consideration.

    Mots-clés Pascal : Antibiotique, Infection nosocomiale, Sensibilité résistance, Isolat clinique, Homme, Epidémiologie, Grèce, Europe, Hôpital, Antibactérien

    Mots-clés Pascal anglais : Antibiotic, Nosocomial infection, Sensitivity resistance, Clinical isolate, Human, Epidemiology, Greece, Europe, Hospital, Antibacterial agent

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0126294

    Code Inist : 002B02S02. Création : 21/05/1997.