Association between breast cancer risk and the intake of vitamins C and E, retinol, beta (bêta) - carotene, dietary fibre, vegetables, fruit and potatoes was examined in The Netherlands Cohort Study, for 62 573 women aged 55-69 years.
After 4.3 years of follow-up, 650 incident breast cancer cases were identified.
After adjusting for traditional risk factors, breast cancer risk was not influenced by the intake of bêta-carotene, vitamin E, dietary fibre, supplements with vitamin C, vegetables or potatoes.
Fruit consumption showed a non-significant inverse association with breast cancer risk (RR highest/lowest quintile=0.76,95% Cl 0.54-1.08).
A small reduction in risk was also observed with increasing intake of dietary vitamin C (RR highest/lowest quintile=0.77,95% Cl 0.55-1.08).
For retinol, a weak positive association was observed (RR highest/lowest quintile=1.24,95% Cl 0.83-1.83).
Among subjects with a high intake of polyunsaturated fatty acids (PUFAs), both bêta-carotene and vitamin C intake showed a non-significant inverse association with breast cancer risk (P-trend=0.15 and 0.16 respectively).
Our findings do not suggest a strong role, if any, for intake of vitamins C and E, bêta-carotene, retinol, dietary fibre, vegetables, fruit and potatoes in the aetiology of breast cancer.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Acide ascorbique, alpha-Tocophérol, Rétinol, Vitamine, Bétacarotène, Fibre alimentaire, Antioxydant, Pomme de terre, Légume, Fruit, Etude cohorte, Pays Bas, Europe, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Ascorbic acid, alpha-Tocopherol, Retinol, Vitamin, Betacarotene, Dietary fiber, Antioxidant, Potato, Vegetable, Fruit, Cohort study, Netherlands, Europe, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0122363
Code Inist : 002B20E02. Création : 21/05/1997.