Despite an international resolution to eliminate neonatal tetanus (NT) as a public health problem by the year 1995,490 000 cases occurred worldwide in 1994.
An analysis of the NT elimination programme in Egypt was conducted to determine the utility of a'high risk'approach in controlling this disease.
Three of the indicators for identifying districts at high risk of NT were evaluated : previous NT rates, tetanus toxoid coverage (TT2+), and urban or rural status.
The reduction in NT incidence from 1992 to 1994 was compared between those high risk districts (=1 NT case/1000 live births in 1992) which did or did not conduct supplementary immunization (P=0.035).
In a multivariate analysis, the strongest indicator of the NT risk in a district was the presence of =1 case/1000 live births in the previous year (Rate ratios [RR]=3.34 in 1993 and 3.07 in 1994, P<0.001).
The TT2+coverage was not a reliable indicator of NT risk.
Urban areas had a significantly lower risk than rural areas (RR=0.62 in 1993 and 0.49 in 1994, P<0.001).
The decline in NT rates was greatest in the'high risk'districts that conducted supplementary immunization in both 1993 and 1994.
Although tetanus toxoid immunization of pregnant women will protect newborns from NT, TT2+coverage calculated by the administrative method may not reflect a population's risk of NT.
Surveillance data, however, can be used to identify areas where the ongoing risk of NT is high. (...)
Mots-clés Pascal : Tétanos, Bactériose, Infection, Néonatal, Vaccination, Prévention, Gestation, Répartition géographique, Efficacité, Surveillance sanitaire, Femme, Homme, Nouveau né, Epidémiologie, Egypte, Afrique, Nouveau né pathologie
Mots-clés Pascal anglais : Tetanus, Bacteriosis, Infection, Neonatal, Vaccination, Prevention, Pregnancy, Geographic distribution, Efficiency, Sanitary surveillance, Woman, Human, Newborn, Epidemiology, Egypt, Africa, Newborn diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0080512
Code Inist : 002B05A02. Création : 21/05/1997.