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  1. Determinants of longevity : genetic, environmental and medical factors.

    Article - En anglais

    This review focuses on the determinants of longevity in the industrialized world, with emphasis on results from recently established data bases.

    Strong evidence is now available that demonstrates that in developed countries the maximum lifespan as well as the mean lifespan have increased substantially over the past century.

    There is no evidence of a genetically determined lifespan of around 85 years.

    On the contrary, the biggest absolute improvement in survival in recent decades has occurred amongst 80+year-olds.

    Approximately one-quarter of the variation in lifespan in developed countries can be attributed to genetic factors.

    The influence of both genetic and environmental factors on longevity can potentially be modified by medical treatment, behavioural changes and environmental improvements.

    Mots-clés Pascal : Longévité, Déterminant, Survie, Facteur milieu, Génétique, Article synthèse, Homme, Pays industrialisé, Espérance vie

    Mots-clés Pascal anglais : Longevity, Determinant, Survival, Environmental factor, Genetics, Review, Human, Industrialized country

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0079744

    Code Inist : 002B30A03A. Création : 21/05/1997.