A retrospective cohort study evaluated the risk of lung cancer in aerospace workers with a minimum of 6 months'employment in jobs with chromium [VI] exposure (n=2429).
Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and cumulative exposure based on industrial hygiene and work-history data.
The overall SIR for lung cancer was 0.8 (observed [Obs]=15).
Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employment as a painter.
Although based on few cases, an elevated lung cancer risk was found in subjects who had worked for 5 or more years as a chrome plater or surface processor tank tender (Obs=2, SIR=1.9) and sander/masker or polisher (Obs=3, SIR=2. 7).
A clear association was not observed between chromate exposure and the risk of lung cancer in this population of workers.
Mots-clés Pascal : Chrome VI, Métal lourd, Exposition professionnelle, Toxicité, Homme, Tumeur maligne, Bronchopulmonaire, Carcinogène, Industrie aérospatiale, Médecine travail, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Chromium VI, Heavy metal, Occupational exposure, Toxicity, Human, Malignant tumor, Bronchopulmonary, Carcinogen, Aerospace industry, Occupational medicine, Epidemiology, United States, North America, America, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0076121
Code Inist : 002B11A. Création : 21/05/1997.