African Americans are at higher risk for lung carcinoma than whites in the United States.
This racial disparity is greater among younger people.
The authors evaluated whether racial differences in lung carcinoma risk can be explained by differences in cigarette smoking behaviors.
For this study, 5588 population-based cases of African Americans and whites with pathologically confirmed lung carcinoma, diagnosed between 1984 and 1987, were identified through the Metropolitan Detroit Cancer Surveillance System.
Also identified were 3692 population-based controls.
Logistic regression methods were used to evaluate the risk of lung carcinoma associated with race both within cigarette smoking category and after adjustment for cigarette-smoking behaviors.
The difference in lung carcinoma incidence between African Americans and whites was explained almost entirely by differences in smoking habits among study participants age 55-84 years.
However, among males age 40-54 years, African Americans were 2-4 times more likely to develop lung carcinoma of any histologic type than whites even after adjustments were made for smoking habits.
Similar excesses in risk among African American females age 40-54 years were demonstrated only for squamous cell and small cell carcinomas (odds ratios [OR] and 95% confidence intervals [CI]=3.7 [1.5-8.91 and 2.7 [1-7.3], respectively). (...)
Mots-clés Pascal : Carcinome, Bronchopulmonaire, Homme, Caucasoïde, Noir américain, Race, Facteur risque, Epidémiologie, Tabagisme, Michigan, Etats Unis, Amérique du Nord, Amérique, Milieu urbain, Incidence, Négroïde, Age, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Tumeur maligne
Mots-clés Pascal anglais : Carcinoma, Bronchopulmonary, Human, Caucasoid, Black American, Race, Risk factor, Epidemiology, Tobacco smoking, Michigan, United States, North America, America, Urban environment, Incidence, Negroid, Age, Respiratory disease, Lung disease, Bronchus disease, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0073949
Code Inist : 002B11A. Création : 21/05/1997.