To define prescribing patterns for symptomatic dyspeptic patients in a cross-section of general practitioners in Leeds, United Kingdom.
Nine general practitioners from a range of practices took part in a prospective observational study of prescribing patterns for dyspepsia.
All consultations with symptomatic dyspeptic patients were recorded over a 4-month period.
Symptoms were recorded as ulcer-like, reflux-like, or nonspecific, and details of recent therapy, previous investigations and any prescription issued were noted.
257 consecutive consultations were recorded (new patients 23%, consulted before but not investigated 33%, previously investigated 44%). 93% of consultations resulted in a prescription (antacids 24%, prokinetic/motility agent 8%, H2-receptor antagonist 36%, proton pump inhibitor 24%, Helicobacter pylori eradication therapy 8%). 42.5% of new patients received an acid-suppressing drug as first-line therapy, of which only 32% had tried over-the-counter remedies.
Symptom-type (ulcer-like, reflux-like or nonspecific) significantly influenced choice of empiric therapy (P<0.001), though prescribing was still variable.
Although around 60% of patients with previously negative investigations or only minor disease received acid-suppressing drugs, such patients were six times more likely to receive'less potent'treatments (no prescription, antacid or motility agent) than those with known acid-peptic disease (odds ratio 6.23, P<0.01). (...)
Mots-clés Pascal : Dyspepsie, Prescription, Médecin généraliste, Homme, Epidémiologie, Etude comparative, Antiacide, Récepteur histaminergique H2, Antagoniste, Motilité, Stimulant, Traitement, Chimiothérapie, Appareil digestif pathologie, Royaume Uni, Europe
Mots-clés Pascal anglais : Dyspepsia, Prescription, General practitioner, Human, Epidemiology, Comparative study, Antiacid, H2 receptor, Antagonist, Motility, Stimulant, Treatment, Chemotherapy, Digestive diseases, United Kingdom, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0072858
Code Inist : 002B02H. Création : 21/05/1997.