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  1. Prevalence of Helicobacter pylori infection and related gastroduodenal lesions in spouses of Helicobacter pylori positive patients with duodenal ulcer.

    Article - En anglais

    Background-To date, very few studies have evaluated the risk of infection among spouses of Helicobacter pylori positive patients and their results are conflicting.

    Aim-To assess the seroprevalence of H pylori infection in spouses of H pylori positive patients with duodenal ulcer as compared with age and sex matched volunteer blood donors, as well as the frequency of endoscopic gastroduodenal lesions in these spouses, according to the presence or absence of gastrointestinal complaints.

    Methods-Some 124 spouses (48% males) of patients with duodenal ulcer consecutively seen over a 10 month period were studied.

    They were all screened for serum IgG anti-H pylori antibodies and asked to complete a questionnaire with particular reference to the presence of chronic or recurrent dyspepsia.

    Upper gastrointestinal tract endoscopy with antral and corpus biopsy specimens taken for histological examination and urease rapid test was offered to all seropositive spouses.

    Volunteer blood donors (248), living in Milan and matched for age, sex, north-south origins, and socioeconomic status to the cases, were used as controls.


    Spouses of patients with duodenal ulcer had a significantly higher seroprevalence of H pylori infection than controls (71% v 58%, p<0.05) ; 30 of 88 (34%) H pylori positive spouses complained of dyspeptic symptoms compared with only four of 34 (12%) seronegative spouses (p<0.02). (...)

    Mots-clés Pascal : Ulcère, Duodénum, Association morbide, Infection, Campylobactériose, Bactériose, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Transmission homme homme, Conjoint, Incidence, Symptomatologie, Etude statistique, Homme, Appareil digestif pathologie, Intestin pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Ulcer, Duodenum, Concomitant disease, Infection, Campylobacter infection, Bacteriosis, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Transmission from man to man, Spouse, Incidence, Symptomatology, Statistical study, Human, Digestive diseases, Intestinal disease, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0070652

    Code Inist : 002B05B02F. Création : 21/05/1997.