Previous studies in Melanesians of Papua New Guinea have documented low serum cholesterol concentrations with no age-related rise and a virtual absence of coronary heart disease.
However, because of recent reports of the emergence of coronary heart disease in this population, serum lipid concentrations in adults aged =25 years in three coastal (n=1,489) and three highland (n=388) village communities at different stages of modernization were examined as part of a survey undertaken in 1991.
Total cholesterol concentrations were clearly higher than were levels recorded in earlier studies.
Moreover, age-related increases in total cholesterol, low density lipoprotein cholesterol (LDL cholesterol), high density lipoprotein cholesterol (HDL cholesterol), and triglycerides (in women) were apparent.
Mean total cholesterol levels in an urban community with a high risk of diabetes were similar to those observed in Australians, while HDL cholesterol concentrations were lower.
Total cholesterol and LDL cholesterol levels were higher in urban coastal and periurban highland subjects than in their rural counterparts.
Prevalence of hypercholesterolemia (=5.2 mmol/liter) varied from 16% in rural highlanders to 56% in urban coastal subjects.
Sex, age, village, body mass index, fat distribution, glucose intolerance, physical activity, and an index of relative modernity all contributed to variations in cholesterol and triglyceride concentrations. (...)
Mots-clés Pascal : Taux, Cholestérol, Triglycéride, Cardiopathie coronaire, Facteur risque, Epidémiologie, Acculturation, Mode de vie, Modernisation, Sang, Papouasie Nouvelle Guinée, Mélanésie, Océanie, Milieu rural, Milieu urbain, Lipide, Appareil circulatoire pathologie, Homme
Mots-clés Pascal anglais : Rate, Cholesterol, Triglyceride, Coronary heart disease, Risk factor, Epidemiology, Acculturation, Life habit, Modernization, Blood, Papua New Guinea, Melanesia, Oceania, Rural environment, Urban environment, Lipids, Cardiovascular disease, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0069954
Code Inist : 002B29A. Création : 21/05/1997.