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  1. 1-hydroxypyrene levels in coal-handling workers at a coke oven.

    Article - En anglais

    An environmental and medical survey was conducted at the coal-handling area of a coke oven, where workers came in contact with coal-tar sludge.

    The purpose of the study was to determine if skin contact with coal-tar sludge was an important route of exposure to pyrene because workers were observed to have substantial contact with the sludge.

    Environmental monitoring revealed minimal airborne exposure to pyrene, a byproduct of the coke distillation process ; only one personal breathing zone sample detected pyrene, and at a level of 0.001 mg/m3.

    However, the mean preshift urinary 1-hydroaypyrene concentration was 1.00 mumol/mol creatinine (range, 0.16 to 2. 96 mumol/mol creatinine) and the mean postshift level was 1.7 mumol/mol creatinine (range, 0.24 to 4.85 mumol/mol creatinine) (P<0.01).

    These levels probably reflect absorption as a result of skin exposure.

    Mots-clés Pascal : Pyrène, Métabolite, Composé aromatique polycyclique, Surveillance biologique, Exposition professionnelle, Goudron houille, Four coke, Homme, Voie administration, Voie externe, Médecine travail

    Mots-clés Pascal anglais : Pyrene, Metabolite, Polycyclic aromatic compound, Biological monitoring, Occupational exposure, Coal tar, Coke oven, Human, Route of administration, Topical administration, Occupational medicine

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0062218

    Code Inist : 002B03L06. Création : 21/05/1997.