An environmental and medical survey was conducted at the coal-handling area of a coke oven, where workers came in contact with coal-tar sludge.
The purpose of the study was to determine if skin contact with coal-tar sludge was an important route of exposure to pyrene because workers were observed to have substantial contact with the sludge.
Environmental monitoring revealed minimal airborne exposure to pyrene, a byproduct of the coke distillation process ; only one personal breathing zone sample detected pyrene, and at a level of 0.001 mg/m3.
However, the mean preshift urinary 1-hydroaypyrene concentration was 1.00 mumol/mol creatinine (range, 0.16 to 2. 96 mumol/mol creatinine) and the mean postshift level was 1.7 mumol/mol creatinine (range, 0.24 to 4.85 mumol/mol creatinine) (P<0.01).
These levels probably reflect absorption as a result of skin exposure.
Mots-clés Pascal : Pyrène, Métabolite, Composé aromatique polycyclique, Surveillance biologique, Exposition professionnelle, Goudron houille, Four coke, Homme, Voie administration, Voie externe, Médecine travail
Mots-clés Pascal anglais : Pyrene, Metabolite, Polycyclic aromatic compound, Biological monitoring, Occupational exposure, Coal tar, Coke oven, Human, Route of administration, Topical administration, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0062218
Code Inist : 002B03L06. Création : 21/05/1997.