Previous studies suggest that colorectal cancer risk decreases with higher intake of vegetables, fruits, and grains.
Few studies, however, have examined these factors in relation to occurrence of colorectal polyps.
The authors used case-control data from 488 matched pairs to evaluate associations of vegetables, fruits, and grains with polyps.
Subjects were southern Califomians aged 50-74 years who had a sigmoidoscopy in 1991-1993.
Diet in the year before sigmoidoscopy was measured with a food frequency questionnaire.
Frequent consumption of vegetables, fruits, and grains was associated with decreased polyp prevalence.
Specifically, the adjusted odds ratio comparing the highest with the lowest quintile of intake for vegetables was 0.47 (95% confidence interval (Cl) 0.29-0.76), for fruits was 0.65 (95% Cl 0.40-1.05), and for grains was 0.55 (95% Cl 0.33-0.91).
The authors also found inverse associations for high carotenoid vegetables, cruciferae, high vitamin C fruits, garlic, and tofu (or soybeans).
After further adjusting for potentially anticarcinogenic constituents of these foods, high carotenoid vegetables, cruciferous vegetables, garlic, and tofu (or soybeans) remained inversely associated with polyps.
These findings support the hypothesis that high intake of vegetables, fruits, or grains decreases the risk of polyps and suggest that any protective effects might reflect unmeasured constituents in these foods.
Mots-clés Pascal : Polype adénomateux, Côlon, Rectum, Epidémiologie, Consommation alimentaire, Comportement alimentaire, Alimentation, Céréale, Légume, Fruit, Homme, Californie, Etats Unis, Amérique du Nord, Amérique, Tumeur bénigne, Côlon pathologie, Rectum pathologie, Intestin pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Adenomatous polyp, Colon, Rectum, Epidemiology, Food intake, Feeding behavior, Feeding, Cereal, Vegetable, Fruit, Human, California, United States, North America, America, Benign neoplasm, Colonic disease, Rectal disease, Intestinal disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0057053
Code Inist : 002B13B01. Création : 21/05/1997.