The human T-lymphotropic virus type II (HTLV-II) has recently been associated with the genesis of some subacute neurological syndromes and, rarely, with atypical T-lymphoid malignancies.
The virus is endemic in some Amerindian and African tribes, and among intravenous drug users (IDUs) in North America and Europe.
Given that HTLV-II is transmitted by the same routes as other human retroviruses, the screening of antibodies to HTLV-II in blood donors has became a matter of controversy in some countries.
Herein, we describe the clinical, epidemiological and virological features of 113 individuals with HTLV-II infection identified in Spain up to September 1995.
Most of them (94/113 ; 83%) were male, and all but seven were natives.
Four were African immigrants living in Madrid and 3 had been born in other European countries.
All but six subjects were IDUs, and sexual transmission of HTLV-II and transfusion were involved in five and one individual, respectively.
Eighty-four percent of the IDUs infected with HTLV-II were co-infected by HIV-1 (93/107).
Clinical manifestations potentially linked to HTLV-II were absent, although an IDU male co-infected by HIV-I and HTLV-II developed a severe non-inflammatory proximal myopathy.
In conclusion, HTLV-II infection is present in Spain, mainly among IDUs, with a growing incidence and a current overall prevalence of 2.0 percent.
Mots-clés Pascal : Virus HTLV2, Retroviridae, Virus, Infection, Symptomatologie, Epidémiologie, Diagnostic, Homme, Espagne, Europe
Mots-clés Pascal anglais : HTLV-II virus, Retroviridae, Virus, Infection, Symptomatology, Epidemiology, Diagnosis, Human, Spain, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0056014
Code Inist : 002B05C02J. Création : 21/05/1997.