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  1. Non-Hodgkin's lymphomas, chronic lymphocytic leukaemias and skin cancers.

    Article - En anglais

    Data from the Cancer Registries of the Swiss Cantons of Vaud and Neuchâtel were analysed to examine possible associations between skin cancers (including basal cell carcinoma, BCC), non-Hodgkin's lymphomas (NHL) and chronic lymphocytic leukaemias (CLL).

    Between 1974 and 1993,1767 cases of NHL, 351 of CLL, 1678 of cutaneous malignant melanoma (CMM), 4131 of squamous cell carcinoma (SCC) and 10 575 of BCC were registered, and contributed to a total of 120103 personyears at risk.

    Following NHL, 36 cases of SCC were registered compared with 5.1 expected, corresponding to a standardised incidence ratio (SIR) of 7.0 (95% confidence interval, CI, 4.9-9.7) ; 37 cases of BCC were observed compared with 10.2 expected (SIR=3.6 ; 95% CI 2.6-5.0).

    Following CLL, nine cases of SCC were observed compared with 1.8 expected (SIR=5.0 ; 95% CI 2.3-9.5) and nine cases of BCC were observed compared with 3.3 expected (SIR=2.7 ; 95% CI 1.2-5.2).

    After SCC, 23 cases at NHL were observed compared with 9.0 expected (SIR=2.6 ; 95% CI 1.6-3.8) ; after BCC, 43 cases of NHL were registered compared with 22.5 expected (SIR=1.9 ; 95% CI 1.4-2.6) ; and after CMM, four cases of NHL were observed compared with 2.0 expected (SIR=2.0).

    No significant excess of CLL was recorded following skin cancer, but the absolute numbers were small and the SIR was above unity. (...)

    Mots-clés Pascal : Leucémie lymphoïde, Lymphome non hodgkinien, Tumeur maligne, Peau, Second cancer, Facteur risque, Rayonnement solaire, Rayonnement UV, Epidémiologie, Registre, Suisse, Europe, Homme, Chronique, Hémopathie maligne, Lymphoprolifératif syndrome, Peau pathologie

    Mots-clés Pascal anglais : Chronic lymphocytic leukemia, Non Hodgkin lymphoma, Malignant tumor, Skin, Second cancer, Risk factor, Solar radiation, Ultraviolet radiation, Epidemiology, Register, Switzerland, Europe, Human, Chronic, Malignant hemopathy, Lymphoproliferative syndrome, Skin disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0050841

    Code Inist : 002B19B. Création : 21/05/1997.