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  1. Symptoms and cholinesterase activity among rural residents living near cotton fields in Nicaragua.

    Article - En anglais

    Objectives-To explore whether symptoms resulted from pesticide spray drift on residentially exposed populations in rural Nicaragua.

    Methods-100 residents, each 10 years of age or older, were randomly selected from a Nicaraguan community surrounded by actively sprayed cotton fields (the exposed community) and from a socioeconomically similar community far from agricultural spraying (the control community).

    Subjects working with pesticides were excluded, and the study was conducted at the end of the 1990 cotton spraying season (August-December).

    Demographic information, exposure questions, and prevalence of 11 acute symptoms and 17 chronic symptoms were gathered from a structured interview.

    Finger stick erythrocyte cholinesterase (AChE) was measured with a portable colorimeter.

    Acute symptoms were grouped according to their previously known associations with cholinesterase (ChE) inhibitors into four ordinal categories (asymptomatic, non-specific, possible, probable).


    Residents from the exposed community were significantly more likely to report recently sighting a spray plane near their community, exposure to pesticide from drift, crossing recently sprayed fields, eating home grown food, and feeling ill after drift exposure.

    The mean AChE value was significantly lower for residents of the exposed community (4.9 v 5.3 IU/dl). (...)

    Mots-clés Pascal : Pesticide, Organophosphoré, Anticholinestérasique, Insecticide, Agriculture, Pulvérisation, Système nerveux pathologie, Toxicité, Non professionnel, Zone résidentielle, Pollution, Milieu rural, Environnement, Homme, Nicaragua, Amérique Centrale, Amérique

    Mots-clés Pascal anglais : Pesticides, Organophosphorus compounds, Anticholinesterase agent, Insecticide, Agriculture, Spraying, Nervous system diseases, Toxicity, Non occupational, Residential zone, Pollution, Rural environment, Environment, Human, Nicaragua, Central America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0046217

    Code Inist : 002B03G. Création : 21/05/1997.