Non-fibrous inorganic particles in bronchoalveolar lavage fluid of pottery workers.
Aim-To study the actual exposure of pottery workers to silica particles, as their risk of silicosis is potentially high because of the presence of inhalable crystalline silica particles in the workplace.
Methods-Nine pottery workers underwent bronchoalveolar lavage.
The recovered fluid was analysed for cytological and mineralogical content by analytical transmission electron microscopy.
The data were compared with those obtained from a control group composed of seven patients with sarcoidosis and six patients with haemoptysis.
Cytological results showed a similar profile in exposed workers and controls, whereas in patients with sarcoidosis a lymphocytic alveolitis was found.
Microanalysis of the particulate identified the presence of silicates, CRSs, and metals.
Pottery workers had higher numbers of total particles and CRSs, and had a higher silicatelmetal ratio.
In five workers, the presence of zirconium silicate was also detected.
Patients with sarcoidosis had the lowest number of particles, and an inverted silicatelmetal ratio.
Conclusion-Microanalysis by transmission electron microscope can provide useful information to assess occupational exposure to dusts.
Mots-clés Pascal : Poussière, Silice, Exposition professionnelle, Silicose, Exploration, Lavage bronchoalvéolaire, Analyse minéralogique, Microscopie électronique transmission, Poterie, Homme, Toxicité, Médecine travail, Italie, Europe, Appareil respiratoire pathologie, Poumon pathologie, Pneumoconiose, Maladie professionnelle
Mots-clés Pascal anglais : Dust, Silica, Occupational exposure, Silicosis, Exploration, Bronchoalveolar lavage, Mineralogical analysis, Transmission electron microscopy, Pottery, Human, Toxicity, Occupational medicine, Italy, Europe, Respiratory disease, Lung disease, Pneumoconiosis, Occupational disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0045272
Code Inist : 002B03L03. Création : 21/05/1997.