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  1. The dynamics of scalet fever epidemics in England and Wales in the 19th century.

    Article - En anglais

    There was a marked rise in scarlet fever mortality in England and Wales in the mid-nineteenth century and spectral analysis of the registration details, 1847-80, shows that the interepidemic interval was 5-6 years, but after 1880 the endemic level fell and the fatal epidemics disappeared.

    The dynamics of the scarlet fever epidemics can be represented by a linearized mathematical model and because the system is lightly damped, it could be driven by an oscillation in susceptibility.

    Epidemics were significantly correlated with dry conditions in spring/summer (P<0.001), suggesting that these produced a low amplitude oscillation in susceptibility which drove the system.

    Epidemics also correlated (P<0.001) with an oscillation in wheat prices but at a tag of 3 years, suggesting that malnutrition during pregnancy caused increased susceptibility in the subsequent children which interacted synergistically with seasonal dry conditions.

    Scarlet fever mortality was sharply reduced after 1880 in parallel with falling wheat prices suggesting that the remarkable period of high scarlet fever mortality (1840-80) was dependent on poor nutritive levels during that time.

    Mots-clés Pascal : Homme, Epidémiologie, Epidémie, Rétrospective, Dynamique, Comportement alimentaire, Scarlatine, Streptococcie, Bactériose, Infection, Angleterre, Grande Bretagne, Royaume Uni, Europe, Pays de Galles, 19ième siecle

    Mots-clés Pascal anglais : Human, Epidemiology, Epidemic, Retrospective, Dynamics, Feeding behavior, Scarlet fever, Streptococcal infection, Bacteriosis, Infection, England, Great Britain, United Kingdom, Europe, Wales

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0044929

    Code Inist : 002A05B11. Création : 21/05/1997.