Numerous disorders are associated with euthyroid sick syndrome (ESS).
This retrospective study examines the incidence and circumstances of ESS among 3188 psychiatric inpatients.
There were 324 patients (10.2%) who met strictly defined criteria for ESS.
Of these, 95 were hyperthyroxinemic (HT), 6 were hypothyroxinemic, 179 had mildly elevated thyroid-stimulating hormone (HTSH), and 47 had suppressed TSH.
All were classified by DSM-III-R discharge diagnoses, encompassing five categories. khi2 tests of significance of the 95 HT and 179 HTSH subjects revealed the following : 1) no relationship with age or gender ; 2) the frequencies of HT and HTSH differed significantly (p<. 05 and p<. 01, respectively) across the five psychiatric categories ; 3) HT frequency was highest in mood disorders (HT in mood versus others p<. 02) ; and 4) HTSH frequency was highest in substance abuse (HTSH in substance abuse versus others p<. 02).
In conclusion, ESS is common in psychiatric inpatients, especially HT and HTSH ; pathophysiologic mechanisms may vary according to psychiatric diagnosis.
Mots-clés Pascal : Euthyroïdie, Association morbide, Trouble psychiatrique, Incidence, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Physiopathologie, Homme
Mots-clés Pascal anglais : Euthyroidism, Concomitant disease, Mental disorder, Incidence, Epidemiology, United States, North America, America, Pathophysiology, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0043915
Code Inist : 002B18C14. Création : 21/05/1997.