To identify factors that explain a lower survival rate among black women with endometrial cancer when compared to white women.
Data are from the National Cancer Institute's Black/White Cancer Survival Study, a population-based study of racial differences in cancer survival.
Subjects included 329 white and 130 black women, ages 20-79 years, residing in the metropolitan areas of Atlanta, New Orleans, or San Francisco-Oakland, diagnosed with endometrial cancer from 1985 to 1987.
Known prognostic factors were assessed as potential explanatory variables for the black-white survival difference using proportional hazards regression.
Information was derived from interviews, abstracts of hospital and physicians'records, and a centralized review of biopsy and surgical specimens.
Adjusting for age and geographic location, risk of death among black women was 4.0 times (95% confidence interval [CI] 2.8,5.6) that of white women.
Approximately 40% of this difference could be attributed to a more advanced stage at diagnosis among black women, and 23% to tumor characteristics and treatment.
Further adjustment for all remaining factors reduced the hazard ratio to 1.6 (95% CI 1.0,2.6). (...)
Mots-clés Pascal : Tumeur maligne, Endomètre, Ethnie, Etude comparative, Pronostic, Survie, Facteur risque, Homme, Femelle, Caucasoïde, Négroïde, Epidémiologie, Appareil génital femelle pathologie, Utérus pathologie
Mots-clés Pascal anglais : Malignant tumor, Endometrium, Ethnic group, Comparative study, Prognosis, Survival, Risk factor, Human, Female, Caucasoid, Negroid, Epidemiology, Female genital diseases, Uterine diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0042615
Code Inist : 002B20C02. Création : 21/05/1997.