To examine the clinical manifestations of 39 patients with temporal (giant cell) arteritis (GCA), allocated during a 10 year period in the largest medical center in Israel.
The patients were included in the analysis if they fulfilled the new American College of Rheumatology Classification Criteria for the diagnosis of GCA.
Patients were divided into biopsy-proven (30 patients) and biopsy-negative (9 patients) groups, and their clinical manifestations were compared using Student's t test for comparison of continuous variables, and Fisher's exact test for comparison of proportions.
The most common presenting symptoms of the patients with TA included headache (87% of the biopsy-proven patients), fever (64%), visual abnormalities (41%), and polymyalgia rheumatica (PMR) or weight loss (20% each).
Ten percent of the biopsy-proven patients presented with occult presentation.
Analysis of biopsy-proven and biopsy-negative groups revealed the feasibility of making the diagnosis of temporal arteritis on the basis of simple clinical variables, even without a positive biopsy, as the 2 groups of patients had comparable manifestations.
However, the biopsy-proven group was older, included more males and presented significantly more with fever, compared to the biopsy-negative patients. (...)
Mots-clés Pascal : Horton maladie, Artérite, Cellule géante, Homme, Epidémiologie, Symptomatologie, Incidence, Israël, Asie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Vascularite, Maladie système, Artère pathologie
Mots-clés Pascal anglais : Giant cell arteritis, Arteritis, Giant cell, Human, Epidemiology, Symptomatology, Incidence, Israel, Asia, Cardiovascular disease, Vascular disease, Vasculitis, Systemic disease, Arterial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0029424
Code Inist : 002B07. Création : 21/05/1997.