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  1. Clinical manifestations of temporal arteritis : A report from Israel.

    Article - En anglais

    Objective

    To examine the clinical manifestations of 39 patients with temporal (giant cell) arteritis (GCA), allocated during a 10 year period in the largest medical center in Israel.

    Methods

    The patients were included in the analysis if they fulfilled the new American College of Rheumatology Classification Criteria for the diagnosis of GCA.

    Patients were divided into biopsy-proven (30 patients) and biopsy-negative (9 patients) groups, and their clinical manifestations were compared using Student's t test for comparison of continuous variables, and Fisher's exact test for comparison of proportions.

    Results

    The most common presenting symptoms of the patients with TA included headache (87% of the biopsy-proven patients), fever (64%), visual abnormalities (41%), and polymyalgia rheumatica (PMR) or weight loss (20% each).

    Pulmonary involvement occurred in 5 patients

    Ten percent of the biopsy-proven patients presented with occult presentation.

    Analysis of biopsy-proven and biopsy-negative groups revealed the feasibility of making the diagnosis of temporal arteritis on the basis of simple clinical variables, even without a positive biopsy, as the 2 groups of patients had comparable manifestations.

    However, the biopsy-proven group was older, included more males and presented significantly more with fever, compared to the biopsy-negative patients. (...)

    Mots-clés Pascal : Horton maladie, Artérite, Cellule géante, Homme, Epidémiologie, Symptomatologie, Incidence, Israël, Asie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Vascularite, Maladie système, Artère pathologie

    Mots-clés Pascal anglais : Giant cell arteritis, Arteritis, Giant cell, Human, Epidemiology, Symptomatology, Incidence, Israel, Asia, Cardiovascular disease, Vascular disease, Vasculitis, Systemic disease, Arterial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0029424

    Code Inist : 002B07. Création : 21/05/1997.