Butadiene epidemiology : a summary of results and outstanding issues.
Evaluation of Butadiene and Isopropene Health Risks. International Symposium. Blaine, Washington (USA), 1995/06/27.
Published epidemiologic studies of butadiene workers, individually and in aggregate, find rates similar to expected for essentially all forms of cancer, with the possible exception of lymphohematopoietic cancers.
Reviewers of the literature have disagreed about whether butadiene is a cause of human lymphohematopoietic cancers.
This article reviews the available butadiene epidemiologic studies and focuses on the bases for disagreement among reviewers.
The disagreement seems to be due to different conventions in applying, explicitly or implicitly, Hill's causal criteria, fostered, in part, by deficiencies in the available epidemiologic studies.
Many of these deficiencies will be remedied by updated studies presented at this Symposium or are remediable by other analyses of the existing data.
Mots-clés Pascal : Butadiène, Carcinogène, Epidémiologie, Lymphome, Homme, Leucémie, Hémopathie maligne, Lymphoprolifératif syndrome
Mots-clés Pascal anglais : Butadiene, Carcinogen, Epidemiology, Lymphoma, Human, Leukemia, Malignant hemopathy, Lymphoproliferative syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0027792
Code Inist : 002B04E02. Création : 21/05/1997.