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  1. Trends in prostate cancer survival in Sweden, 1960 through 1988 : Evidence of increasing diagnosis of nonlethal tumors.

    Article - En anglais

    Background 

    The incidence of prostate cancer has increased during the past 30 years but has been paralleled by increases in survival rates from this disease, despite the absence of documented major improvement in curative treatment.

    Since a high prevalence of microscopic prostate cancer has been observed in autopsied men and because many prostate cancers may never surface clinically, increased diagnostic activities might have led to increased detection of less aggressive tumors.

    Purpose 

    This study was conducted to elucidate whether the trends in prostate cancer incidence and patient survival may be due to increasing diagnoses of nonlethal tumors.

    Methods 

    We analyzed a population-based cohort comprising all cases of prostate cancer (n=80 901) detected in Sweden during the period of 1960 through 1988.

    Five hundred eighteen patients (0.64% of the total number) who could not be followed because of emigration or an incomplete national registration number were excluded.

    Observed and relative survival rates were calculated for the entire cohort of 80383 assessable patients per 5-year age group in 5-year periods of diagnosis and according to diagnostic method and were compared between geographic areas with differences in incidence rates.

    To estimate the independent effects of these determinants, multivariate analyses were performed.

    Results 

    For the 80383 patients with complete follow-up, the 10-and 20-year observed survival rates were 17. (...)

    Mots-clés Pascal : Tumeur maligne, Prostate, Homme, Pronostic, Survie, Incidence, Epidémiologie, Analyse tendance, Etude longitudinale, Suède, Europe, Appareil génital mâle pathologie, Appareil urinaire pathologie, Prostate pathologie

    Mots-clés Pascal anglais : Malignant tumor, Prostate, Human, Prognosis, Survival, Incidence, Epidemiology, Trend analysis, Follow up study, Sweden, Europe, Male genital diseases, Urinary system disease, Prostate disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0026578

    Code Inist : 002B14D02. Création : 21/05/1997.