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  1. Antimicrobial resistance of Streptococcus pneumoniae : Comparison of the in vitro activity of 16 antibiotics.

    Article, Communication - En anglais

    Infectious Diseases Forum, Roussel'93. Symposium. Acapulco (MEX), 1993/09/02.

    A selected sample of 492 strains of Streptococcus pneumoniae (175 susceptible, 142 intermediately resistant, and 175 highly resistant to penicillin) isolated from adult patients in Bellvitge Hospital, Barcelona, Spain, was tested for susceptibility to 16 antibiotics using a microdilution broth method.

    Imipenen, rifampin, vancomycin, cefpirome, cefotaxime, and amoxicillin were the most active antibiotics against penicillin-resistant pneumococci.

    The strains with intermediate or high resistance to penicillin exhibited a significantly greater percentage of resistance (P ¾ 0.05) to erythromycin, clindamycin, tetracycline, chloramphenicol, and cotrimoxazole than penicillin-susceptible pneumococci.

    No resistance to third-generation cephalosporins was detected among penicillin-susceptible strains, whereas 1.4% of intermediately resistant strains and 13.2% of penicillin-resistant strains showed minimal inhibitory concentrations of cefotaxime = 2 mug/mL.

    Mots-clés Pascal : Antibiotique, Antibactérien, Sensibilité résistance, Streptococcus pneumoniae, Streptococcaceae, Micrococcales, Bactérie, Test sensibilité médicamenteuse, In vitro, Isolat clinique, Homme, Hôpital, Espagne, Europe, Infection communautaire

    Mots-clés Pascal anglais : Antibiotic, Antibacterial agent, Sensitivity resistance, Streptococcus pneumoniae, Streptococcaceae, Micrococcales, Bacteria, Drug susceptibility test, In vitro, Clinical isolate, Human, Hospital, Spain, Europe, Community acquired infection

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0017218

    Code Inist : 002B02S02. Création : 21/05/1997.