Among adults with mental retardation, mortality rates for those with Down syndrome are higher than for those without Down syndrome.
We studied age-related changes in functioning and their relation to subsequent mortality in adults with mental retardation.
Among people without Down syndrome, recent loss of basic skills was associated with substantially elevated mortality rates.
This was not so in the Down syndrome group, however.
Adults with Down syndrome tended to experience regression in adaptive behavior earlier than did those without Down syndrome.
Incidence rates in the two groups diverged subsequent to age 40.
Adults without Down syndrome, however, did also tend to regress when older.
Mots-clés Pascal : Arriération mentale, Trouble développement, Mortalité, Trisomie, Aneuploïdie, Aberration chromosomique, Chromosome G21 anormal, Chromosome anormal, Mongolisme, Facteur risque, Epidémiologie, Incidence, Aptitude, Homme, Déficience intellectuelle
Mots-clés Pascal anglais : Mental retardation, Developmental disorder, Mortality, Trisomy, Aneuploidy, Chromosomal aberration, Abnormal chromosome G21, Abnormal chromosome, Down syndrome, Risk factor, Epidemiology, Incidence, Ability, Human, Intellectual deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0015222
Code Inist : 002B18C12. Création : 21/05/1997.