Bronchial hyperresponsiveness in active coke-oven workers.
Coke-oven workers are exposed to dust and irritant gases.
Therefore they are at risk of developing lung diseases including chronic bronchitis.
Non specific bronchial hyperresponsiveness (BHR) has been advocated as a potential risk factor predisposing to the development of chronic bronchitis.
In a preliminary study, we showed that retired coke-oven workers had a higher prevalence of BHR than retired blast-furnace workers.
The present study was carried out to determine the prevalence of BHR in active steel-workers.
Thus, 124 coke-oven workers and 59 blast-furnace workers were studied and underwent clinical examination, standardized questionnaire for the study of respiratory symptoms, pulmonary function test and methacholine aerosol challenge.
The study demonstrates an increased prevalence of BHR in coke-oven workers (36.2% ; 95% CL 27.5-44.9) compared to blast-furnace workers (12.5% ; 95% CL 3.8-21.2).
Moreover, BHR was significantly more frequent in coke-oven workers with respiratory symptoms or basal bronchial obstruction.
The basal maximum expiratory flow 25-75 and the respiratory symptoms were correlated with BHR.
However, the high proportion of steelworkers who smoked, the workers turn-over in the steel plant, and the « Healthy Worker Effect » could explain the lack of association observed between BHR and the intensity of smoking or years spent in coke-oven area.
Mots-clés Pascal : Poussière, Gaz, Exposition professionnelle, Hypersensibilité, Bronche, Bronchite, Chronique, Four coke, Fonderie acier, Homme, Toxicité, Médecine travail, Appareil respiratoire pathologie, Bronche pathologie
Mots-clés Pascal anglais : Dust, Gases, Occupational exposure, Hypersensitivity, Bronchus, Bronchitis, Chronic, Coke oven, Steel foundry, Human, Toxicity, Occupational medicine, Respiratory disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0010832
Code Inist : 002B03L03. Création : 21/05/1997.