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  1. Methadone maintenance treatment and HIV risk-taking behaviour among injecting drug users in Berlin.

    Article - En anglais

    Study objective

    To determine whether methadone maintenance treatment (MMT) is effective in reducing the levels of HIV risk-taking behaviour (borrowing and lending of injection equipment, irregular condom use) among injecting drug users (IDUs), and to identify independent predictors of the borrowing of used syringes.


    Cross sectional study of IDUs in MMT and not in MMT, using standardised interviews for collection of sociodemographic and behavioural data, and laboratory tests for detecting HIV antibodies.

    Setting and participants

    The 612 IDUs were recruited at different services for drug users such as treatment centres, walk in agencies, a hospital, and on the streets.

    Main results Of all IDUs, 41% had borrowed and 34% had passed on used injection equipment in the previous six months.

    In univariate analysis, IDUs receiving MMT had injected less frequently and were significantly less likely to borrow and lend syringes.

    In logistic regression analysis, MMT was protective against the borrowing of syringes (adjusted odds ratio 0.36,95% confidence interval 0.2,0.8), but not against syringe lending nor against sexual risk behaviour (ie, numbers of sex partners, lack of condom use).

    Important independent predictors of the borrowing of syringes were injecting drug use in prison, use of sedatives, and sex with another IDU in the previous six months.


    MMT may play a significant role in reducing the levels of borrowing of syringes among IDUs. (...)

    Mots-clés Pascal : SIDA, Virose, Infection, Prise risque, Toxicomanie, Voie intraveineuse, Homme, Méthadone, Traitement substitutif, Chimiothérapie, Epidémiologie, Seringue, Partage, Condom, Comportement sexuel, Opiacés, Immunopathologie, Immunodéficit, Allemagne, Europe

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Risk taking, Drug addiction, Intravenous administration, Human, Methadone, Replacement therapy, Chemotherapy, Epidemiology, Syringe, Sharing, Condom, Sexual behavior, Opiates, Immunopathology, Immune deficiency, Germany, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0009474

    Code Inist : 002B06D01. Création : 21/05/1997.