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  1. Relation between the longitudinal development of lipoprotein levels and biological parameters during adolescence and young adulthood in Amsterdam, The Netherlands.

    Article - En anglais

    Study objectives

    To analyse the relation between the longitudinal development of total serum cholesterol (TC), high density lipoprotein cholesterol (HDL), and the TC/HDL ratio and the longitudinal development of the biological parameters body fatness (SSF), lean body mass (LBM), and cardiopulmonary fitness (VO2-max).

    The relations were analysed with generalised estimating equations (GEE).


    The relations were investigated with data from the Amsterdam growth and health study, a longitudinal study in which six measurements were carried out within a period of 15 years.


    Altogether 98 females and 84 males aged 13 years at the start of the study.

    Main results

    Adjusted for lifestyle and other biological parameters, the longitudinal development ofTC was inversely related to the development of LBM (standardised regression coefficient bêta=-0.27 ; p ¾ 0.01) and positively to SSF (bêtamales=0.32 ; p¾0.01 and bêtafemales=0.15 ; p¾0.01).

    HDL was inversely related to LBM (bêta=-0.26 ; p¾0.01) and positively to VO2-max (bêta=0.08 ; p¾0.05).

    The TC/HDL ratio was positively related to SSF (bêtamales=0.39 ; p¾0.01 and bêtafemales=0.13 ; p¾0.01) and inversely to VO2-max (bêta=-0.09 ; p¾0.05).


    The longitudinal analyses showed that body fatness was related to a high risk profile with respect to hypercholesterolaemia, and cardiopulmonary fitness to a low risk profile. (...)

    Mots-clés Pascal : Cholestérol, Cholestérol HDL, Lipoprotéine, Fitness, Consommation oxygène maximum, Appareil respiratoire, Lipide, Indice masse corporelle, Biométrie corporelle, Epidémiologie, Adolescent, Homme, Adulte jeune, Mode de vie, Pays Bas, Europe

    Mots-clés Pascal anglais : Cholesterol, Cholesterol HDL, Lipoprotein, Fitness, Maximum oxygen consumption, Respiratory system, Lipids, Body mass index, Corporal biometry, Epidemiology, Adolescent, Human, Young adult, Life habit, Netherlands, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0009467

    Code Inist : 002B29A. Création : 21/05/1997.