In cross-sectional analyses, serum cholesterol levels differ among different age groups.
However, secular time trends in cholesterol levels can be seen across age groups in a population.
A birth cohort analysis provides useful information on the combined effect of age and time on changes in serum cholesterol levels.
To analyze the 20-year dynamics of serum total cholesterol levels in relation to age, sex, birth cohort, time period, mortality rate, and changes in the intake of saturated fats.
Cross-sectional measurements of serum total cholesterol levels in five independent population surveys done in 1972,1977,1982,1987, and 1992.
Kuopio and North Karelia provinces in eastern Finland.
Random sample of 16711 men and 17542 women 25 to 64 years of age.
Persons in the oldest birth cohort were born in 1913 ; persons in the youngest birth cohort were born in 1967.
Total serum cholesterol levels and daily intake of dietary fat.
Between 1972 and 1992, mean cholesterol levels decreased with time in each age group and for both sexes.
According to the cross-sectional data, cholesterol levels increased with age and increased more steeply in women than in men.
Contrary to these data, cholesterol levels in birth cohorts did not increase with age.
Cholesterol levels did not change at all within birth cohorts of women and started to decrease after 45 years of age in birth cohorts of men. (...)
Mots-clés Pascal : Cholestérol, Etude transversale, Etude cohorte, Echantillonnage aléatoire, Population, Dosage, Régime alimentaire, Finnois, Recommandation alimentaire, Dépistage, Graisse insaturée, Prévention, Facteur risque, Homme, Complication, Lipide, Métabolisme pathologie, Organisation santé
Mots-clés Pascal anglais : Cholesterol, Cross sectional study, Cohort study, Random sampling, Population, Assay, Diet, Finnish, Dietary allowance, Medical screening, Unsaturated fat, Prevention, Risk factor, Human, Complication, Lipids, Metabolic diseases, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0007403
Code Inist : 002B22A. Création : 21/05/1997.