SYNOPSIS The Virginia Twin-Family Study of Adolescent Behavioral Development (VTSABD) is a current longitudinal study of psychopathology in 1412 pairs of 8-16-year-old Caucasian twins and their parents.
The primary aim of the study is to evaluate family-genetic and environmental risk factors for major domains of psychopathology in families representative of the Virginia Caucassian population.
In this report, we utilize census-derived indices of neighbourhood income and urban residence to identify departures from population representation arising at the time of family enrolment in the twin registry and family participation in a psychiatric interview.
Furthermore, we consider whether demographic sample biases influenced prevalence rates of adult psychopathology (including major depression, generalized anxiety disorder, alcohol dependence, phobias, and panic disorder) in the VTSABD.
Results indicated that families that enrolled in the twin registry (83% of those identified by Virginia schools) and that participated in the home interview (75% of those targeted) resided in urban and rural communities with a range of per capita income levels representative of the Virginia population.
However, participation biases operated throughout the study and were primarily characterized by losses of families living in low income, urban communities. (...)
Mots-clés Pascal : Trouble psychiatrique, Adolescent, Homme, Etude familiale, Etiologie, Interaction génotype environnement, Enquête, Epidémiologie, Virginie, Etats Unis, Amérique du Nord, Amérique, Etude longitudinale, Jumeau, Biais méthodologique, Participation, Méthodologie, Démographie
Mots-clés Pascal anglais : Mental disorder, Adolescent, Human, Family study, Etiology, Genotype environment interaction, Survey, Epidemiology, Virginia, United States, North America, America, Follow up study, Twin, Methodological bias, Participation, Methodology, Demography
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0004036
Code Inist : 002B18C14. Création : 21/05/1997.