Risk factors for lower respiratory complications of rhinovirus infectious in elderly people living in the community : prospective cohort study.
To assess the role of rhinoviruses in elderly people living in the community.
Design-Prospective community based surveillance of elderly people, without intervention.
Subjects were telephoned weekly to identify symptomatic upper respiratory tract infections.
Symptoms and impact of illnesses were monitored, and specimens were collected for diagnostic serology and human rhinovirus polymerase chain reaction.
Subjects-533 subjects aged 60 to 90.
Main outcome measures-Symptoms, restriction of activity, medical consultations, and antibiotic use during 96 rhinovirus infections.
Adjusted odds ratios for lower respiratory syndromes with respect to smoking and health status.
A viral cause was established in 211 (43%) of 497 respiratory illnesses ; rhinoviruses were identified in 121 (24%) and as single pathogens in 107.
The median duration of the first or only rhinovirus infection in the 96 people with 107 rhinovirus infections was 16 days ; 18 of the 96 patients were confined to bed and 25 were unable to cope with routine household activities.
Overall, 60 patients with rhinovirus infections had lower respiratory tract syndromes ; 41 patients consulted their doctor, 31 of them (76%) receiving antibiotics.
One patient died
Mots-clés Pascal : Rhinovirus, Picornaviridae, Virus, Virose, Infection, Voie respiratoire, Complication, Facteur risque, Vieillard, Homme, Etude cohorte, Prospective, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Rhinovirus, Picornaviridae, Virus, Viral disease, Infection, Respiratory tract, Complication, Risk factor, Elderly, Human, Cohort study, Prospective, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0003607
Code Inist : 002B05C02C. Création : 21/05/1997.