European Meeting of Environmental Hygiene. Prague (CZE), 1995/06/27.
The present study aimed to investigate immune parameters in sera of adult persons chronically exposed to different degrees of ambient air pollution.
As related to air pollution derived from coal mining industry and coke plants, a significantly increased prevalence of cases with abnormally high serum levels of the immunoglobulins IgA and IgM as well as the complement component C3c was found as compared with a less polluted control area, indicating a higher stimulation of acute reactants in combination with a polyclonal immune response.
These findings may be attributed to elevated concentrations of airborne particulates, suggesting that permanent exposure to increased levels of airborne particulates leads to chronic irritation of the airways in association with activation of the immune system, which may give rise to an enhanced risk for chronic airway diseases.
Mots-clés Pascal : Toxicité, Système immunitaire, Immunopathologie, Homme, Adulte, Chronique, Pollution air, Marqueur biologique, Epidémiologie, Allemagne, Europe, Zone industrielle, Méthode étude, Analyse chimique, Immunoglobuline, Sérum sanguin
Mots-clés Pascal anglais : Toxicity, Immune system, Immunopathology, Human, Adult, Chronic, Air pollution, Biological marker, Epidemiology, Germany, Europe, Industrial area, Investigation method, Chemical analysis, Immunoglobulins, Blood serum
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0002763
Code Inist : 002B03M02. Création : 21/05/1997.