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  1. Characteristics of lung cancer in the elderly.

    Article - En anglais

    In order to define the characteristics of lung cancer in the elderly, 260 patients with lung cancer were retrospectively analyzed according to their age group ; group A=¾ 49 years (n=19), group B=50-69 years (n=152), and group C== 70 years (n=89).

    The ratio of male to female increased with age from 1.4 (group A), 3.9 (group B) to 7.1 (groupC).

    In males, the percentage of squamous cell carcinoma increased from 18% in group A, 30% in group B to 54% in group C. Conversely, in females adenocarcinoma was constantly high for all groups (100%, 71%, 91%). There was no significant difference in the distribution of the clinical stage of the disease among the three groups.

    The percentage of patients undergoing surgery was lowest for group C with 15% compared to the two other groups with 32% and 28%, respectively.

    Conversely, the percentage of patients receiving only the best supportive care was highest for group C with 24% (0% in group A, 10% in group B).

    The prognosis for the patients in group C was significantly poorer than for the other groups ; median survival time was 12.5,10.0 and 7.0 months, with a 3-year survival rate (%) of 7.8,19.4 and 6.3% in groups A, B, and C, respectively.

    Male and squamous cell type were characteristic of lung cancer in the elderly, apparently supporting the idea that cigarette smoking plays a role in lung carcinogenesis, and the necessity of early establishment of an optimal therapeutic strategy for lung cancer in the elderly was indicated.

    Mots-clés Pascal : Carcinome, Bronchopulmonaire, Adulte, Homme, Vieillard, Age, Etude comparative, Epidémiologie, Japon, Asie, Type histologique, Stade clinique, Pronostic, Traitement, Sexe, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Tumeur maligne, Anatomopathologie

    Mots-clés Pascal anglais : Carcinoma, Bronchopulmonary, Adult, Human, Elderly, Age, Comparative study, Epidemiology, Japan, Asia, Histological type, Clinical stage, Prognosis, Treatment, Sex, Respiratory disease, Lung disease, Bronchus disease, Malignant tumor, Pathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0002333

    Code Inist : 002B11A. Création : 21/05/1997.