The influence of study characteristics on the healthy worker effect : A multiple regression analysis.
The so-called'healthy worker effect' (HWE) describes a reduced mortality rate in occupational populations.
From 85 occupational cohorts of workers exposed to organic solvents, we have previously found a low weighted standardized mortality ratio (SMR) for all causes (SMR=89.5,95 per cent confidence interval [CI]=89.0-90.2).
Characteristics of the cohorts were examined for association with the HWE.
A multiple regression analysis revealed that, for overall deaths, the closer the comparison group, the smaller the HWE (p=0.001) ; the more hazardous the potential exposures, the higher the SMR (p=0.02) ; the higher the social class, the greater the HWE (p=0.02) ; and the higher the rates of loss to follow up, the greater the HWE (p=0.04).
These results have shown that, in addition to time-related modifiers, the comparison group, type of occupational exposure, social class and rates of loss to follow-up significantly influence the size of the so-called HWE.
Differences in the HWE related to gender and race were probably attributable to different rates of loss to follow-up.
Mots-clés Pascal : Adaptation, Poste travail, Condition travail, Mortalité, Exposition professionnelle, Solvant organique, Homme, Etude cohorte, Statut socioéconomique, Médecine travail, Régression multiple, Analyse régression, Effet du travailleur en bonne santé
Mots-clés Pascal anglais : Adaptation, Workplace layout, Working condition, Mortality, Occupational exposure, Organic solvent, Human, Cohort study, Socioeconomic status, Occupational medicine, Multiple regression, Regression analysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0500897
Code Inist : 002B03L04. Création : 10/04/1997.