The baseline examination (1987-1989) for the Atherosclerosis Risk in Communities (ARIC) Study was conducted in 15,792 free-living residents aged 45-64 years in four geographically dispersed US communities.
A questionnaire on symptoms of transient ischemic attack (TIA) and stroke was evaluated by computer algorithm for 12,205 of these participants.
Data were also collected on lipoprotein levels, hemostasis, hematology, anthropometry, blood pressure, medical history, lifestyle, socioeconomic status, and medication use.
Noninvasive high resolution B-mode ultrasonographic imaging was used to determine carotid arterial intimal-medial wall thickness (IMT).
The cross-sectional relation between the prevalence of TIA/stroke symptoms and putative risk factors was assessed by logistic regression, controlling for age and community.
Odds ratios for TIA/stroke symptoms were significantly elevated (p<0.01) for diabetes mellitus, current smoking, hypertension, lower levels of education, income, and work activity, and higher levels of lipoprotein (a), IMT, hemostasis factor VIII, and von Willebrand factor.
However, the relations with education and carotid IMT were not present for black Americans.
In whites, the relations of TIA/stroke symptoms to IMT were nonlinear.
Only at extreme levels of IMT were symptoms substantially more frequent : For example, men with an IMT greater than 1.17 mm or women with an IMT greater than 0. (...)
Mots-clés Pascal : Accident cérébrovasculaire, Ischémie, Encéphale, Epidémiologie, Facteur risque, Algorithme, Simulation ordinateur, Questionnaire, Symptomatologie, Etats Unis, Amérique du Nord, Amérique, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Stroke, Ischemia, Brain (vertebrata), Epidemiology, Risk factor, Algorithm, Computer simulation, Questionnaire, Symptomatology, United States, North America, America, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0499078
Code Inist : 002B17C. Création : 10/04/1997.