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  1. Analyses of cost effectiveness in the management of essential hypertension : What they can and what they do not teach us.

    Article - En anglais

    There are approximately 50 million hypertensive individuals in the United States, and their treatment is often life-long.

    Most are asymptomatic, so the goal of treatment is to prevent complications, which often occur decades after the condition is detected.

    Although the management of hypertension is potentially very costly, it is now clear that antihypertensive therapy can substantially reduce cardiovascular mortality and morbidity.

    This constellation of an asymptomatic process with a very high prevalence capable of producing severe and potentially costly complications is precisely the circumstance under which cost effectiveness of therapy becomes an important consideration.

    Several such analyses have been performed, examining the question of which patients should be treated, what procedures should be used in their evaluation, and which therapeutic agents should be used.

    These studies highlight important issues, but also illustrate the potential pitfalls and fallacies of such analyses, particularly when outcome data are unavailable or inadequate.

    This article reviews the literature concerning cost-effectiveness analyses in the management of hypertension and discusses the value of this approach.

    Mots-clés Pascal : Hypertension artérielle, Antihypertenseur, Analyse coût efficacité, Etats Unis, Amérique du Nord, Amérique, Traitement, Evaluation, Homme, Article synthèse, Appareil circulatoire pathologie, Chimiothérapie

    Mots-clés Pascal anglais : Hypertension, Antihypertensive agent, Cost efficiency analysis, United States, North America, America, Treatment, Evaluation, Human, Review, Cardiovascular disease, Chemotherapy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0493141

    Code Inist : 002B12B05B. Création : 10/04/1997.