logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Human immunodeficiency virus infection and other risk factors for skin abscesses and endocarditis among injection drug users.

    Article - En anglais

    Objective 

    To study incidence rates of and risk factors for skin abscesses at the site of injection and episodes of endocarditis among injection drug users (IDU).

    Design 

    A comprehensive, open cohort study of drug users on the natural history of human immunodeficiency virus (HIV) infection.

    Methods 

    From 1986 to 1994, injection drug users in Amsterdam were included in the study.

    Incidence rates of self-reported skin abscesses and verified episodes of endocarditis were calculated.

    In uni-and multivariate Poisson regression analysis, risk factors for skin abscesses and endocarditis were determined.

    Results 

    521 HIV-seronegative and 237 HIV-seropositive IDU were followed for 1640 person-years.

    A total of 545 skin abscesses were reported by 269 IDU (incidence 33/100 person-years).

    HIV infection, female gender, prostitution among females, foreign nationality, injection of heroin and cocaine, a high frequency of injecting, and obtaining syringes through the needle exchange program were independently and positively associated with skin abscesses.

    During follow-up, 17 verified episodes of endocarditis were observed (incidence 1.3/100 person-years).

    Endocarditis was independently associated with HIV infection and a previous history of endocarditis.

    Furthermore, women and IDU with a skin abscess appeared to be at an increased risk for endocarditis.

    Conclusions 

    HIV infection is an independent risk factor for skin abscesses and endocarditis. (...)

    Mots-clés Pascal : Endocardite, Abcès, Peau, Toxicomanie, Voie intraveineuse, SIDA, Virose, Infection, Facteur risque, Epidémiologie, Site injection, Homme, Pays Bas, Europe, Appareil circulatoire pathologie, Cardiopathie, Endocarde pathologie, Peau pathologie, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Endocarditis, Abscess, Skin, Drug addiction, Intravenous administration, AIDS, Viral disease, Infection, Risk factor, Epidemiology, Injection site, Human, Netherlands, Europe, Cardiovascular disease, Heart disease, Endocardial disease, Skin disease, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0489105

    Code Inist : 002B08J. Création : 10/04/1997.