Objectives The purpose of this study was to describe hematopoietic and reproductive hazards of Korean electronic workers exposed to solvents containing 2-bromopropane.
Methods Detailed medical and occupational histories were taken and thorough physical examinations with clinical laboratory tests were done for 33 workers (8 men and 25 women).
Previous and present exposure was investigated in detail by industrial hygienists.
Results Of the 25 female workers, 16 were shown to have secondary amenorrhea with high follicle-stimulating hormone levels, normal prolactin levels, and hot flashes.
A total of eight workers with amenorrhea concurrently showed findings of pancytopenia.
Among eight male workers, two showed azoospermia and another four showed some degree of oligospermia (normal>20 million ml-1) or reduced sperm motility (normal>50%). The bone marrow effects and the testis or ovarian failure was shown to be the main health hazards in this workplace.
Except for the cleaning solution containing 97.4% 2-bromopropane, no other known physical or chemical agents could be identified as responsible for the gonadal and bone marrow effects, including ionizing radiation, lead, ethylene glycol ether and its acetates, benzene, and dibromochloropropane. (...)
Mots-clés Pascal : Solvant organique, Exposition professionnelle, Toxicité, Industrie électronique, Oligospermie, Sperme, Reproduction, Hémopathie, Hormone stéroïde, Corée du Sud, Corée, Asie, Médecine travail, Homme, Appareil génital mâle pathologie, Sperme pathologie, Appareil génital femelle pathologie, Ovaire pathologie, Propane(2-bromo)
Mots-clés Pascal anglais : Organic solvent, Occupational exposure, Toxicity, Electronics industry, Oligospermia, Semen, Reproduction, Hemopathy, Steroid hormone, South Korea, Korea, Asia, Occupational medicine, Human, Male genital diseases, Semen disorders, Female genital diseases, Ovarian diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0477836
Code Inist : 002B03L04. Création : 10/04/1997.