Brain tumor risk in offspring of men occupationally exposed to electric and magnetic fields.
Objectives The purpose of the study was to address the possible associations between the occupational exposure of men to electromagnetic fields (EMF) and the risk of childhood brain tumors in offspring by reanalyzing case-referent interview data from a study of environmental factors and childhood brain tumors conducted by one of the authors and first reported in 1990.
Methods Analyses of the case-referent data were limited to the 94 cases and 166 individually-matched referents for whom data on the biological fathers were available.
Paternal exposure to occupational EMF was inferred from a list of job titles compiled for that purpose.
Mantel-Haenszel odds ratios (OR) for individually matched cases and referents were estimated for different definitions of exposure.
Results The findings suggested at best very small increases in risk for jobs associated with the occupational EMF exposure of fathers during the one-year period prior to conception, the OR values ranging from 1.12 to 1.31.
Notably elevated OR values were, however, found in association with any paternal welding in the one-year preconception period (OR 3.8,95% confidence interval 0.95-15.55).
Conclusions The results of reanalysis indicate that preconceptional paternal occupational exposure to EMF is at best only weakly associated with a risk of childhood brain tumors.
However, the findings for paternal welding are somewhat intriguing since relatively strong EMF have been measured in association with welding. (...)
Mots-clés Pascal : Tumeur maligne, Encéphale, Enfant, Homme, Descendance, Exposition professionnelle, Père, Champ électromagnétique, Toxicité, Médecine travail, Encéphale pathologie, Système nerveux central pathologie, Système nerveux pathologie
Mots-clés Pascal anglais : Malignant tumor, Brain (vertebrata), Child, Human, Progeny, Occupational exposure, Father, Electromagnetic field, Toxicity, Occupational medicine, Cerebral disorder, Central nervous system disease, Nervous system diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0476753
Code Inist : 002B17E. Création : 10/04/1997.