A case-control study of risk factors for seropositivity to human T-lymphotropic virus type I (HTLV-I) in Jamaica.
We investigated behavioural and environmental risk factors for seropositivity to human T-lymphotropic virus type I (HTLV-I).
A nested case-control study of 201 HTLV-I seropositive subjects and 225 age-and sex-matched seronegative controls was performed using questionnaire data from the enrolment visit of a cohort study in 1987-1988.
HTLV-I serostatus was confirmed using enzyme-linked immunosorbent assay (ELISA) and Western blot.
Among women, the number of lifetime sexual partners (P<0.05, khi2 trend) and the number of different men fathering a child by the woman (P<0.06, khi2 trend) were associated with HTLV-I seropositivity.
Use by the female subject of an intrauterine device (IUD) was associated with an increased risk of seropositivity (odds ratio (OR)=2.67,95% confidence interval (CI) : 1.13-6.23) ; condom use was rare in this population.
Among male subjects, a larger number of lifetime sexual partners was also associated with HTLV-I seropositivity (P<0.05, khi2 trend).
No association was found between HTLV-I seropositivity and educational attainment, income, or occupation.
Having been breastfed as a child or receipt of a blood transfusion had elevated but imprecise OR due to very high and low prevalence of the risk factors, respectively.
Several variables relating to insect or animal exposure showed no association with HTLV-I seropositivity.
Mots-clés Pascal : Virose, Infection, Virus HTLV1, Retroviridae, Virus, Epidémiologie, Homme, Facteur risque, Jamaïque, Antilles, Amérique Centrale, Amérique, Relation sexuelle, Partenaire sexuel, Condom, Age, Sexe, Statut socioéconomique, Séropositivité
Mots-clés Pascal anglais : Viral disease, Infection, HTLV-I virus, Retroviridae, Virus, Epidemiology, Human, Risk factor, Jamaica, West Indies, Central America, America, Sexual intercourse, Sex partner, Condom, Age, Sex, Socioeconomic status, Seropositivity
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0476265
Code Inist : 002B05C02J. Création : 10/04/1997.