Overall cancer incidence not increased after prosthetic knee replacement : 14,551 patients followed for 66,622 person-years.
It is unknown whether patients as a consequence of prosthetic joint replacement are at a higher risk of developing cancer.
We therefore analyzed cancer incidence following prosthetic knee replacement (TKR).
The observed cancer incidence in 14,551 patients from the population-based Swedish Knee Arthroplasty Register who have undergone TKR because of osteoarthrosis (OA, n=10,120) or rheumatoid arthritis (RA, n=4431) were compared with the expected cancer incidence for a Swedish reference population.
The cohort was followed for a total of 66,622 person-years.
We followed 33% of the patients with OA and 59% of those with RA for more than 5 years.
All patients who underwent TKR, whether for OA or for RA, had lower than expected total cancer incidence.
We found a markedly low incidence of colorectal carcinoma, especially in patients with RA.
Our results do not indicate an increased incidence of cancer following TKR.
Mots-clés Pascal : Tumeur maligne, Incidence, Epidémiologie, Facteur risque, Prothèse, Genou, Etude cohorte, Suède, Europe, Homme, Chirurgie
Mots-clés Pascal anglais : Malignant tumor, Incidence, Epidemiology, Risk factor, Prosthesis, Knee, Cohort study, Sweden, Europe, Human, Surgery
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0475206
Code Inist : 002B04B. Création : 10/04/1997.