The vitamin A status of Zambian children attending an under five clinic as evaluated by the modified relative dose response (MRDR) test.
The vitamin A status of 87 children, 7-29 months of age, who were randomly selected from attendees at a pediatric clinic in Ndola, Zambia, were evaluated by the modified relative dose response (MRDR) test.
By using a MRDR ratio cut-off point of 0.06,78% of the children had inadequate vitamin A status.
Both male and female children were equally affected.
Of those with inadequate vitamin A status, 82% were between 7-19 months of age.
A significant inverse relationship (p<0.005) existed between vitamin A inadequacy and Z scores for height for age, weight for age and weight for height.
Children with lower Z scores showed a better vitamin A status in comparison to those with a higher Z score.
This unexpected relationship is probably due to an increased demand for vitamin A in children with a higher weight and rapid growth rate.
Serum vitamin A values correlated poorly with MRDR values except at extreme ends of the distribution.
Although clinical vitamin A deficiency is relatively infrequent in Zambia, we conclude that the vitamin A status of our children nonetheless needs to be improved.
Mots-clés Pascal : Zambie, Afrique, Nourrisson, Homme, Rétinol, Etat nutritionnel, Méthode mesure, Relation dose réponse, Surveillance sanitaire, Alimentation, Vitamine
Mots-clés Pascal anglais : Zambia, Africa, Infant, Human, Retinol, Nutritional status, Measurement method, Dose activity relation, Sanitary surveillance, Feeding, Vitamin
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0474795
Code Inist : 002B29B. Création : 10/04/1997.