Deliberations and evaluations of the approaches, endpoints and paradigms for iron dietary recommendations.
Workshop on New Approaches, Endpoints and Paradigms for RDAs of Mineral Elements. Grand Forks, ND USA, 1995/09/10.
Iron deficiency severe enough to cause anemia is associated with significant morbidity while uncontrolled iron absorption which occurs in disorders such as hereditary hemochromatosis causes multiorgan failure and early death.
Preliminary data from the Third National Health and Nutrition Examination Survey demonstrate that the prevalence of iron deficiency anemia in the United States is now very low.
This implies that the current iron consumption is adequate for most individuals.
An important unresolved question relates to the necessity for further reducing the prevalence of iron deficiency without anemia.
More information is required to determine whether this lesser degree of iron deficiency is harmful.
Recent survey data indicate that concomitantly with the reduced prevalence of iron deficiency there has been a rise in serum ferritin concentrations in American men and postmenopausal women.
These findings have led to concern about the effectiveness of the physiological mechanisms for limiting storage accumulation in normal individuals and carriers of the hemochromatosis gene when dietary iron content is high.
Furthermore, recent epidemiological observations suggest that a modest increase in iron stores (in a range previously considered safe) is a possible risk factor for ischemic heart disease and cancer ; however, a causal relationship remains to be proven. (...)
Mots-clés Pascal : Congrès, Article synthèse, Recommandation alimentaire, Fer, Nutrition, Elément minéral, Micronutriment, Alimentation, Homme
Mots-clés Pascal anglais : Congress, Review, Dietary allowance, Iron, Nutrition, Inorganic element, Micronutrient, Feeding, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0474524
Code Inist : 002B30A02A. Création : 10/04/1997.