logo BDSP

Base documentaire

  1. Occupational exposure during nitric oxide inhalational therapy in a pediatric intensive care setting.

    Article - En anglais


    To determine the amount of occupational exposure to nitric oxide (NO) and nitrogen dioxide (NO2) during NO inhalational therapy.


    In a standard pediatric intensive care room, 800 ppm NO was delivered to a high-frequency oscillator and mixed with 100% O2 to obtain 20 ppm NO in the inspiratory gas flow.

    NO and NO2 concentrations in room air were measured using a chemiluminescence analyzer.

    Air samples were taken from a height of 150 cm at a horizontal distance of 65 cm from the ventilator in a nonventilated and in a well-ventilated room with and without an expiratory gas exhaust under normal intensive care environmental conditions.


    Pediatric intensive care unit in a university children's hospital.

    Measurements and results 

    Maximal concentrations of NO and NO2 were reached after 4 h NO use.

    Without exhaust, in a nonventilated room, environmental NO and NO2 concentration rose to a maximum of 0.462 and 0.064 ppm, respectively.

    With the use of an expiratory gas exhaust, NO and NO2 concentrations were 0.176 and 0.042 ppm, respectively.

    With normal air-conditioning, these values were 0.075 and 0.034 ppm, respectively, without the use of an expiratory gas exhaust.

    With expiratory gas exhaust added to normal air-conditioning, values for NO and NO2 were 0.035 and 0.030 ppm, respectively. (...)

    Mots-clés Pascal : Ventilation mécanique, Azote monoxyde, Azote dioxyde, Unité soin intensif, Pédiatrie, Exposition professionnelle, Personnel sanitaire, Médecine travail, Toxicité, Long terme, Homme, Ventilation artificielle, Réanimation respiratoire, Soin intensif

    Mots-clés Pascal anglais : Mechanical ventilation, Nitrogen monoxide, Nitrogen dioxide, Intensive care unit, Pediatrics, Occupational exposure, Health staff, Occupational medicine, Toxicity, Long term, Human, Artificial ventilation, Respiratory intensive care, Intensive care

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0471835

    Code Inist : 002B03L02. Création : 10/04/1997.