To determine the amount of occupational exposure to nitric oxide (NO) and nitrogen dioxide (NO2) during NO inhalational therapy.
In a standard pediatric intensive care room, 800 ppm NO was delivered to a high-frequency oscillator and mixed with 100% O2 to obtain 20 ppm NO in the inspiratory gas flow.
NO and NO2 concentrations in room air were measured using a chemiluminescence analyzer.
Air samples were taken from a height of 150 cm at a horizontal distance of 65 cm from the ventilator in a nonventilated and in a well-ventilated room with and without an expiratory gas exhaust under normal intensive care environmental conditions.
Pediatric intensive care unit in a university children's hospital.
Maximal concentrations of NO and NO2 were reached after 4 h NO use.
Without exhaust, in a nonventilated room, environmental NO and NO2 concentration rose to a maximum of 0.462 and 0.064 ppm, respectively.
With the use of an expiratory gas exhaust, NO and NO2 concentrations were 0.176 and 0.042 ppm, respectively.
With normal air-conditioning, these values were 0.075 and 0.034 ppm, respectively, without the use of an expiratory gas exhaust.
With expiratory gas exhaust added to normal air-conditioning, values for NO and NO2 were 0.035 and 0.030 ppm, respectively. (...)
Mots-clés Pascal : Ventilation mécanique, Azote monoxyde, Azote dioxyde, Unité soin intensif, Pédiatrie, Exposition professionnelle, Personnel sanitaire, Médecine travail, Toxicité, Long terme, Homme, Ventilation artificielle, Réanimation respiratoire, Soin intensif
Mots-clés Pascal anglais : Mechanical ventilation, Nitrogen monoxide, Nitrogen dioxide, Intensive care unit, Pediatrics, Occupational exposure, Health staff, Occupational medicine, Toxicity, Long term, Human, Artificial ventilation, Respiratory intensive care, Intensive care
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0471835
Code Inist : 002B03L02. Création : 10/04/1997.