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  1. Postal survey on the long-term use of neuromuscular block in the intensive care.

    Article, Communication - En anglais

    Joint meeting of the Intensive Care Society and Société de Réanimation de Langue Française. Brighton GBR, 1995/05.


    To assess the long-term use of neuromuscular blocking (NMB) agents in intensive care, expecially with reference to the potential problems of the long-term use of NMB drugs in the intensive care unit (ICU).


    A postal survey questionnaire was sent to 409 ICUs in Great Britain.


    Two hundred thirty-eight completed questionnaires were returned and analysed.

    Most ICUs were anaesthetist-led (85.8%) with only five ICUs being staffed by full-time intensivists.

    Facilitation of mechanical ventilation and increased intracranial pressure were the main indications for the prolonged use of neuromuscular blockade.

    Atracurium and vecuronium (83%) were administered most commonly by bolus alone (13.8%), bolus followed by continuous infusion (23.9%) or continuous infusion only (60.9%). The most frequently cited criteria for the use of either vecuronium or stracurium were their pharmacokinetics and haemodynamic stability.

    Neuromuscular block was most commonly monitored clinically (91.7%), with only 8.3% of the responders using a peripheral nerve stimulator.

    All responders indicated the concomitant use of sedatives (propofol/midazolam alone or in combination in 89.4% of responders) and/or opioids (morphine, fentanyl or alfentanil in 74.8% of respondents) with muscle relaxants.


    Most responders agreed that while neuromuscular block in the ICU population may provide advantages, it cannot be considered benign. (...)

    Mots-clés Pascal : Curarisation, Curarisant, Unité soin intensif, Pratique professionnelle, Anesthésiste, Questionnaire, Evaluation, Homme, Grande Bretagne, Royaume Uni, Europe, Long terme, Anesthésie, Soin intensif, Médecin

    Mots-clés Pascal anglais : Neuromuscular blocking, Neuromuscular blocking agent, Intensive care unit, Professional practice, Anesthesiologist, Questionnaire, Evaluation, Human, Great Britain, United Kingdom, Europe, Long term, Anesthesia, Intensive care, Physician

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0471064

    Code Inist : 002B02B08. Création : 10/04/1997.